No nucleus, no problem – platelet biology and scientific communication

S3E13 - No nucleus, no problem – platelet biology and scientific communication

Published: July 9, 2025

Duration: 30:12

In this episode of Speaking of Mol Bio, Dr. Beth Webb takes us deep into the world of platelets, often misunderstood components of blood that punch far above their weight in both physiological and pathological processes. As a postdoctoral researcher at the University of Leeds, Dr. Webb explores how endothelial signals influence platelet activity, and how these anucleate cell fragments play roles not only in clotting, but also in immune responses, inflammation, and diseases like cardiovascular disorders and COVID-19.

Beth unpacks the technical challenges of isolating and analyzing platelets—particularly in RNA sequencing and qPCR—while stressing the...