Chorio Paradox: When Clinical & Path DX Don’t Agree

Chorio Paradox: When Clinical & Path DX Don’t Agree

Published: December 21, 2025

Duration: 23:36

Welcome to "Labor & Delivery Debrief," the podcast where we tackle your toughest questions about childbirth and maternal health. Today, we're diving deep into a fascinating and critical topic sent in by one of our listeners, Sarah. Sarah asks: "Is it possible for a clinical diagnosis of chorioamnionitis to not be confirmed by placental histology? And if so, how is that possible?" This is a fantastic question that touches on the complexities of intrapartum clinical diagnosis of intraamniotic infection (IAI), also commonly known as chorioamnionitis. We'll explore the nuances of clinical versus histological findings, the diagnostic criteria, and why these two...
Chorio Paradox: When Clinical & Path DX Don’t Agree - Dr. Chapa’s OBGYN Clinical Pearls