E330 - Lipofuscin: Cellular Kryptonite That Nobody Talks About

There is a lot of talk about autophagy, or cellular recycling, and apoptosis, programmed cell death, in relationship to circadian rhythm entrainment, ketogenic diets, and intermittent fasting. What I never hear is people talking about lipofuscin, the intracellular kryptonite and shuts down both of those processes by gumming up the lysosomes of our cells. When the garbage recycling center of our cells gets up to 75% full of this nearly non-degradable material, our mitochondria, cell, and tissue function fails.

In this episode I focus on the exact biochemical mechanisms of how lipofuscin causes harm, not just being an...