E144 - Autism, Microbiomes, & Mice Burying Marbles with Kevin Mitchell

This week, we are joined by Kevin Mitchell, Associate Professor of Genetics and Neuroscience at Trinity College Dublin, who has committed the unforgivable sin of pointing out that an entire academic and media hype cycle might be built on… well, very little actually. His new co-authored paper in Neuron politely dismantles the highly promoted link between the gut microbiome and autism, which turns out to rest on flawed studies, contradictory findings, creative statistics, and a touching faith in mice burying marbles.

Kevin walks us through the joys of observational studies that don’t replicate, mouse experiments that don...